Searchable abstracts of presentations at key conferences in endocrinology

ea0015p252 | Pituitary | SFEBES2008

Adjustment for macroprolactin: an integral part of laboratory assessment of hyperprolactinaemia

Blantern Liz , Qureshi Zubair , Heald Adrian , Anderson Simon , Radford Daniela , Waldron Julian , Davies Marten , McCulloch Alan , Kane John

Background: In most people, prolactin circulates predominantly as a 23-kDa monomer, and a high-molecular-weight form which in the vast majority of cases consists of a complex of prolactin and an anti-prolactin IgG autoantibody, commonly referred to as macroprolactin. This cross-reacts with conventional laboratory assays for prolactin.Report: In a consecutive series of 218 patients with prolactin elevated to 400 μ/l or more in men (normal range &#880...